Relation between proliferation score and ROIs

Hello,

Is the proliferation score (example 0.29) assigned based on only ROIs (i.e. I can exclude the non-ROI region for training)?

Thanks,
Abhishek Vahadane

Hi Abishek, I assume you are talking about the molecular proliferation score. It is based on the mean RNA expression of 11 proliferation-associated genes. It is based on the entire tissue sample (not just the ROIs), but you can assume that most of the image features that relate to this score should be found in the ROIs. Hope that this clarifies it.

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